P2P methamphetamine, or super meth, is now the most prevalent chemical form of meth in the US. And it's changing the face of addiction.

February 14, 2023

Updated June 12, 2025

Super meth, also known as P2P methamphetamine, has become increasingly popular over the past decade due to its purity and the intense, long-lasting highs experienced by those who use it.

The popularity of this meth variant has become a significant public health concern and is linked to numerous adverse physical and psychological health effects, ranging from extreme aggression to paranoia.

By 2012, 96% of DEA samples of methamphetamine were manufactured using the P2P method.

Unfortunately, without efforts from law enforcement, public health organizations, and drug rehab centers, super meth's grip on society will only grow.

The 2006 Turning Point That Changed Everything

When U.S. drug legislation pushed ephedrine and pseudoephedrine behind pharmacy counters in 2006, meth cartels completely reinvented their processes. The result was a more potent, more plentiful, and more affordable version of standard methamphetamine.

And it started with an old method that had been nearly forgotten. This was the birth of today’s super meth.

Frequently Asked Questions

What Is Super Meth?

Super meth (P2P meth) is a variant of standard methamphetamine that uses a different precursor for production. Instead of ephedrine or pseudoephedrine, super meth is manufactured with phenyl-2-propanone (phenylacetone).

What Are the Dangers of Super Meth?

Pre-2006 meth caused euphoric and energizing highs lasting around 12 hours, but super meth causes a stupefying and incapacitating high for 24 hours or more.

P2P meth can cause organ damage, decreased brain function, and overdoses that often lead to death with much smaller doses than conventional meth.

Can the Sweat Patch Detect P2P Meth?

The PharmChek® Drugs of Abuse Sweat Patch can detect super meth with the same accuracy as standard meth. Our 24-hour detection is just as effective for this new threat.

How Does Super Meth Affect Recovery Programs?

The side effects of super meth are more devastating to physical and mental health, and the recovery time prior to starting behavioral treatment is much longer.

Additionally, there are no chemical treatments available at this time. The treatment community is still working to meet the unique needs of P2P meth use recovery.

How Does the Sweat Patch Help Recovery Programs for Super Meth Users?

With an extended wait time before behavioral treatments and with no chemical treatments, sobriety is a key factor in recovery.

PharmChek® provides continuous monitoring with uninterrupted sample collection, long-term wearability, and a tamper-evident design, bridging the gap between challenges and solutions for P2P meth use and abuse.

The Origins of Super Meth

Methamphetamine has been widely produced since the 1920s. There are several different processes that meth manufacturers have used throughout the last 100 years, but the most prevalent process from the 1980s until 2005 used ephedrine or pseudoephedrine as the precursors.

This method replaced the former method, P2P, which was the primary process during the 1970s after amphetamines were rescheduled as Schedule II drugs and before phenylacetone was rescheduled in 1980.

The Combat Methamphetamine Epidemic Act

But everything changed in 2006 when the Combat Methamphetamine Epidemic Act of 2005 was signed into law, making pseudoephedrine and ephedrine much more difficult to purchase in larger quantities. As a result, many meth labs were dismantled throughout the U.S., but Mexican super meth labs started experimenting with the long-abandoned P2P meth production method.

This led to the birth of Mexican cartel meth, today’s super meth, and the start of a new epidemic in methamphetamine use.

The history of super meth starts back in 2006, when the Combat Methamphetamine Epidemic Act of 2005 was signed into law, pushing meth production into Mexico and changing the production method to P2P meth instead of pseudoepehdrine and ephedrine methods.

P2P Methamphetamine: Same Drug, New Formula

Super meth is produced with a much more readily available chemical precursor than ephedrine. This version of meth utilizes phenyl-2-propanone, or P2P, which is commonly used for several legal industrial applications, instead of ephedrine, a plant-derived compound used as a decongestant and stimulant.

Also known as phenylacetone, this compound has long been used to create nasal decongestants like Benzedrex (propylhexedrine), as well as cleaning agents and stain removers.

Why Super Meth Dominates the Market

With a dramatic increase in its prevalance, super meth has taken control of the methamphetamine market. Between the considerably lower meth production costs and the more potent product, it’s the go-to method for cartel manufacturing. And it’s hitting the US hard in southern states, with signs of moving north quickly in the coming years.

Less Expensive, Higher Yields

Because of the chemical simplicity of phenyl-2-propanone, manufacturers use several processes to make this illicit drug. And because the ingredients used to make super meth are so inexpensive and readily available, a 50% yield of P2P (500mL produced per 1kg of phenylacetic acid) is considered cost-effective. However, other meth production methods can produce as much as 90% yields, with relatively little heat and no special equipment to achieve the chemical reaction.

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More Prevalent and Potent Than Past Formulas

Super meth has flooded the market. In fact, the DEA found P2P meth in 96% of their samples by 2012, only 6 years after ephedrine was restricted. Border drug seizures have also increased exponentially year-over-year, rising from only 50 pounds seized at the US-Mexico border in 1998 to almost 131,000 pounds in 2022, an increase of 2,620% over the 24-year period. Mexican super meth lab cartels have seen profits skyrocket as they produce enough P2P meth to crash the established market value and close down small meth labs across the United States.

As super meth production ramped up, seizures for meth at the US-Mexico border skyrocketed. Today, the US market is saturated with p2p meth from Mexico's cartels.

Sources: DEA.gov (NDTA reports for 2008, 2013, 2020); DEA Press Release on 2022 seizures.

How Is Super Meth Different?

The chemical makeup of any methamphetamine includes two separate isomerisms (variants) of the main chemical compound: d-methamphetamine and l-methamphetamine. The d-meth causes euphoric psychoactive effects, while the l-meth typically increases heart rate but does little to provide a high.

Super Meth vs Traditional Meth: Key Differences

Purity is a key differentiator between traditional meth and super meth. The meth purity level is determined as a ratio between the d-meth and l-meth within a sample. In recent drug seizures, l-methamphetamine is almost completely absent in P2P meth, whereas in traditional meth d-methamphetamine concentration is anywhere from 20% to 50% or more.

Higher Purity, Higher Potency

With as much as 96% purity (up from an average of 39% purity in 2008), P2P meth is dangerously potent, even in small amounts. Law enforcement agencies and the United States DEA note higher overdose death rates with super meth than ephedrine-derived meth. Likewise, this new form of methamphetamine is considerably more addictive, providing more intense highs in less time that reportedly last up to 24 hours with a single dose.

In 24 years, methamphetamine's average potency increased from 39% to 93%.

Greater Risk of Physical and Psychological Effects

Alongside the more intense and longer-lasting high, super meth causes more severe physical and mental effects. These effects include increased blood pressure and respiratory rate, elevated body temperature, and the potential for heart attacks or strokes, to name a few.

But unlike past iterations of meth, P2P meth’s reduced concentration of l-methamphetamine eliminates the early physical warning signs of overdose, including elevated heart rate. The result is that meth overdose rates are increasing across the country.

Both the physical and mental side effects of super meth can be long-lasting, sometimes even irreparable. Users not only experience organ stress and potential failure, but they may also find themselves in the midst of paranoid episodes, psychosis, hallucinations (frequent reports of the feeling of bugs crawling under the skin), and memory loss.

Side Effects of Super Meth (Methamphetamine synthesized with Phenyl-2-Propanone)

Physical Side Effects Psychological Side Effects
Jumbled Speech Psychosis
Increased Blood Pressure Violent Paranoia
Increased Respiratory Rate Isolating Behavior
Elevated Body Temperature Hallucinations
Insomnia Delusions
Cardiovascular Issues (heart attack, stroke) Massive Memory Loss
Tremors and Convulsions Anxiety
Death Aggression and Violence

What Is the Social Impact of P2P Meth?

In both Tucson, AZ, and Atlanta, GA, P2P meth has become ubiquitous. But it’s more than just our southern cities that suffer: the easy and prolific production of P2P methamphetamine has made it readily available in almost every corner of the country. And one journalist who has reported on super meth nationwide, Sam Quinones, believes it’s a driving factor intensifying the homelessness crisis throughout the nation.

Increased Isolating Responses to Effects

Old meth formulations, according to Quinones, were "kind of a euphoric drug, a party drug, a social drug, making you want to spend a lot of time around people and so on." But the new formulation is just the opposite.

From Sam Quinones: "On the contrary, what it seems to breed is a very sinister kind of schizophrenia, horrible paranoia, great amounts of hallucinations, and with that…comes homelessness."

"On the contrary, what it seems to breed is a very sinister kind of schizophrenia, horrible paranoia, great amounts of hallucinations, and with that…comes homelessness."

Some users have said that on older versions of meth, they could hold jobs, keep payments current for housing and transportation, and generally maintain their lives. But once super meth became their preferred substance, their social connection to sober individuals was severed by these psychotic and paranoid episodes.

Homelessness and Loss of Support from Community

According to clinical psychologist Nicolas Taylor, this separation drives further addiction and socioeconomic struggles. Without a sober support system, users will instead separate themselves from people who could help them overcome. And Quinones supports this assertion in his field reporting.

In an interview with Dave Miller of OPB News, Quinones states:

"Homelessness is a complicated thing, and there are various kinds of homelessness, but the tent encampment homeless, I would submit, has enormously to do with drug addiction and primarily nowadays with this new meth coming out. It is very well associated with this now."

More Affected Communities Than Ever Before

The reach of super meth has now expanded to the upper east coast, where meth abuse is still a new epidemic compared to other parts of the United States. Even more concerning is that much of the supply of P2P meth is laced with deadly fentanyl.

It's a common practice, especially in the production of counterfeit Adderall pills. In fact, DEA agents have reported that as many as four of every ten fake pills seized today contain lethal doses of meth, fentanyl, or both.

This new mental and social health crisis will have far-reaching impacts on both communities and the justice system. And how each of these entities responds will determine how much damage super meth will have in the future.

With its higher yields and purity, P2P meth has saturated US markets, including massive increases in seizures nationwide. In the Omaha Division of the DEA alone, agents have seen an almost 500% increase in seizures between 2005 and 2019.

How the Sweat Patch Combats the Abuse of Super Meth

Our nation depends on law enforcement and courts to stop the spread of this destructive new meth variant. Improved treatment-based sentencing, rehabilitation, and user accountability within the judicial system will help this epidemic lose steam.

And that accountability will require systems and methods that aid recovery and reintegration vs. punishment and incarceration for super meth users.

Continuous Drug Testing vs Conventional Drug Testing

One proven accountability measure is continuous drug testing. Recovery is not a straight path, and relapse is a common problem. Judges and case workers can help those suffering from drug addiction and dependence by setting routine drug testing that provides accountability and an incentive for staying clean.

Drug testing provides transparency for behavioral modification therapies, including contingency management and motivational enhancement therapies, when used with counseling and community support measures.

Limitations of Traditional Drug Testing and Screening Methods

Most drug testing methods, however, come with critical roadblocks to consistency and accountability. Urinalysis is incredibly invasive of the individual's privacy, and several testing methods require repeat appointments to record substance use accurately.

With many court orders requiring up to three screenings per week, people working towards stability will likely struggle to meet the demands on their schedules without sacrificing their financial stability. Additionally, family care becomes a concern when in-person observation is necessary for accurate testing.

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The Sweat Patch: A Different Approach to Recovery

The PharmChek® Drugs of Abuse Sweat Patch circumvents all of these issues. Its design allows courts and case workers to continuously monitor drug use for up to seven to ten days, or longer, between appointments for specimen collection. The Sweat Patch is a perfect solution for those with housing, job, or transportation insecurities.

Why Is Continuous Screening Important for Super Meth Users?

With its addictive and life-threatening potency, relapse for super meth users poses a dangerous threat for overdose. And with a short metabolization window (around three days at most), meth use could slip through intermittent screening methods if appointments are missed or are too infrequent.

The PharmChek® Sweat Patch provides continuous sample collection through insensible sweat and keeps individuals accountable for potential drug use at all times. Through constant accountability, case workers and judges can help prevent serious medical issues, further social and economic insecurity, and even loss of life from relapses.

Meth prices were much higher before 2012, but with the ease of production for super meth and p2p meth, today's per-dose price is lower than ever.

Sources: Justice.gov archives (2002 and 2003); DEA.gov (2005); iowa.gov (2007); ojp.gov (2008-2009); unodc.org (2010); Statista.com (2012-2017); themountaineer.com (2018); fherehab.com (2019); dovetail.org (2020); pacificsandsrecovery.com (2021); recoveryohio.org (2022); guardianrecoverynetwork.com (2023).

Super Meth Use Recovery Beyond Drug Screening

Drug testing is only one facet of a more complex recovery process. Those suffering from addiction to super meth need counseling services, psychiatric assistance, and support from a sober community to maintain their sobriety.

The severe psychoactive effects of P2P methamphetamine, which lead to social isolation and psychosis in many cases, will take a comprehensive recovery program to overcome these obstacles and reconnect super meth users to the people they love most.

When considering treatment for super meth addiction, keep in mind the need for consistency, accountability, and community. Recovery programs for meth users can see progress in all these areas with the help of the PharmChek® Sweat Patch.


Featured Image Courtesy of MSN.com